LOTUS

A Wikidata hosted open natural products occurrences database

https://lotus.naturalproducts.net/

Acknowledgments

What is LOTUS ?

How did we built LOTUS ?

	Structure	Organism	Reference
Before curation	Cyathocaline	Stem bark of Cyathocalyx zeylanica CHAMP. ex HOOK. f. & THOMS. (Annonaceae)	Wijeratne E. M. K., de Silva L. B., Kikuchi T., Tezuka Y., Gunatilaka A. A. L., Kingston D. G. I., J. Nat. Prod., 58, 459-462 (1995).
After curation	VFIIVOHWCNHINZ-UHFFFAOYSA-N	Cyathocalyx zeylanicus	10.1021/NP50117A020

Structure

Organism

Reference

Before curation

Cyathocaline

Stem bark of Cyathocalyx zeylanica CHAMP. ex HOOK. f. & THOMS. (Annonaceae)

Wijeratne E. M. K., de Silva L. B., Kikuchi T., Tezuka Y., Gunatilaka A. A. L., Kingston D. G. I., J. Nat. Prod., 58, 459-462 (1995).

After curation

VFIIVOHWCNHINZ-UHFFFAOYSA-N

Cyathocalyx zeylanicus

10.1021/NP50117A020

Why LOTUS for metabolomics?

Metabolites annotation!

Arabidopsis example

Beta-sitosterol example

Double dissemination

Double dissemination

LNPN

Wikidata

Queries

Original question

---- "Hey Wikidata, Which organisms are known to contain quercetin (REFJWTPEDVJJIY-UHFFFAOYSA-N)?" ----

SPARQL translation

---- SELECT DISTINCT ?parent_taxon ?parent_taxonname ?taxon ?taxonname WHERE {
VALUES ?classes { wd:Q11173 wd:Q59199015 } ?compound wdt:P31 ?classes; wdt:P235 "REFJWTPEDVJJIY-UHFFFAOYSA-N".
?taxon wdt:P171 ?parent_taxon. { ?compound p:P703 ?stmt.
?stmt ps:P703 ?taxon. { ?stmt prov:wasDerivedFrom ?ref.
?ref pr:P248 ?art. ?art wdt:P356 ?art_doi.
} } ?taxon wdt:P225 ?taxonname.
?parent_taxon wdt:P225 ?parent_taxonname.} ----

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